Feel 5mg Tablet

✔️ Uses of Feel 5mg Tablet

It is used to treat:

• Erectile Dysfunction
• benign prostatic Hyperplasia (BPH)
• Pulmonary Arterial Hypertension (PAH)

✔️ How does Feel 5mg Tablet work?

Feel 5mg Tablet works by relaxing the smooth muscles in the penis and increasing the blood flow. This helps the penis to harden and leads to an erection. Feel 5mg Tablet also relaxes the muscles present in the prostate gland and bladder. Thus, it helps to improve the symptoms of BPH such as increased urinary frequency, difficulty in urination, slow urine stream, etc.

✔️ Side Effects of Feel 5mg Tablet

• Headache
• Back pain
• Muscle pain
• Pain in legs and arms
• Nasal congestion
• Indigestion
• Facial flushing

✔️ Erectile Dysfunction:

Erectile dysfunction, often referred to as impotence, is a condition characterized by the inability to achieve or maintain a firm and rigid erection suitable for sexual intercourse. This condition can be attributed to various factors, including physical and psychological causes. Some common underlying causes of erectile dysfunction include:

Psychological Factors: Anxiety, fear of sexual failure, depression, low self-esteem, and high levels of stress can contribute to erectile dysfunction. These emotional and psychological factors may interfere with the sexual response.

Lifestyle Factors: Certain lifestyle choices such as smoking, excessive alcohol consumption, being overweight or obese, leading a sedentary (inactive) lifestyle, and having high blood pressure can contribute to the development of erectile dysfunction.

The symptoms of erectile dysfunction may include:

• Difficulty in achieving an erection
• Difficulty in maintaining an erection during sexual activity
• Decreased sexual desire or interest

✔️ Benign Prostatic Hyperplasia (BPH):

Benign prostatic hyperplasia, also known as prostate enlargement, is a non-cancerous condition characterized by the abnormal growth of cells within the prostate gland. This enlargement of the prostate gland can lead to various urinary problems. Key aspects of BPH include:

• Cell Multiplication: BPH results from the multiplication of cells within the prostate gland. As these cells multiply, they cause the prostate gland to enlarge, which can result in swelling and compression of the urethra.

Common symptoms of BPH include:

• Loss of bladder control
• Frequent urination
• Inability to initiate urination
• Incomplete bladder emptying
• Weak urinary stream
• Dribbling at the end of the urinary stream
• Sudden and urgent need to urinate
• Painful urination

✔️ Pulmonary Arterial Hypertension (PAH):

Pulmonary arterial hypertension (PAH) is a condition characterized by high blood pressure in the arteries of the lungs and heart. This occurs when the blood vessels in the lungs become narrowed or blocked, leading to increased strain on the heart. Key points about PAH include:

• Symptoms: Symptoms of PAH can include chest pain, dizziness, fatigue, and swelling in the legs and ankles. The narrowed or blocked blood vessels in the lungs reduce the ability of the heart to pump blood efficiently.

✔️ Pharmacology

Tadalafil is a PDE5 (phosphodiesterase type 5) inhibitor that increases cGMP levels in smooth muscle cells. This elevation in cGMP relaxes smooth muscles and enhances blood flow to the corpus cavernosum, leading to penile erection. PDE5 is also present in the smooth muscles of the prostate and bladder wall. Inhibiting PDE5 increases cGMP levels, causing relaxation of smooth muscles in the prostate and bladder. This relaxation can improve blood flow to the urinary system and widen the bladder neck's opening, making voiding more efficient.

✔️ Dosage of Feel 5mg Tablet

Here are the recommended adult doses for Tadalafil (the active ingredient in Feel 5mg Tablet) for different conditions:

Erectile Dysfunction:

For Use as Needed: The starting dose is usually 10 mg, taken before anticipated sexual activity. It can be adjusted to 20 mg or reduced to 5 mg based on efficacy and tolerability. The maximum dosing frequency is once per day.

For Once Daily Use: The starting dose is 2.5 mg, taken at approximately the same time every day, regardless of sexual activity. It can be increased to 5 mg based on individual response.

✔️ Benign Prostatic Hyperplasia (BPH):

BPH: 5 mg taken orally once daily.

BPH with Erectile Dysfunction: 5 mg taken orally once daily, at approximately the same time each day, without regard to sexual activity. If using finasteride for BPH, it's 5 mg of Tadalafil plus 5 mg of finasteride once daily for less than 26 weeks.

✔️ Pulmonary Arterial Hypertension:

• Pulmonary Arterial Hypertension: 40 mg taken orally once daily. It is not recommended to divide the dose for more frequent dosing.

✔️ Hepatic Impairment (Erectile Dysfunction):

Mild-to-Moderate Hepatic Impairment (Child-Pugh class A or B): Do not exceed 10 mg taken orally once daily.

Severe Hepatic Impairment (Child-Pugh class C): Not recommended.

Hepatic Impairment (Pulmonary Arterial Hypertension):

Mild-to-Moderate Hepatic Impairment (Child-Pugh class A or B): Consider starting with 20 mg taken orally once daily.

Severe Hepatic Impairment (Child-Pugh class C): Avoid use.

✔️ Renal Impairment (Erectile Dysfunction):

Mild Renal Impairment (CrCl >51 mL/min): No dosage adjustment is needed.

Moderate Renal Impairment (CrCl 30-50 mL/min): Do not exceed 5 mg taken orally once daily initially; the maximum dosage is 10 mg taken orally every 48 hours.

Severe Renal Impairment (CrCl <30 mL/min and on hemodialysis): Do not exceed 5 mg taken orally every 72 hours.

✔️ Renal Impairment (Pulmonary Arterial Hypertension):

Mild-to-Moderate Renal Impairment (CrCl 31-80 mL/min): Start with 20 mg taken orally once daily; may increase to 40 mg once daily based on tolerability.

Severe Renal Impairment (CrCl <30 mL/min and on hemodialysis): Avoid use.

✔️ Directions for Use of Feel 5mg Tablet

• Take Feel 5mg Tablet as directed by your doctor.
• Swallow the tablet whole with a glass of water.
• Try to take it at the same time each day as advised by your doctor for best results.
• For erectile dysfunction, take it at least 30-60 minutes before sexual activity, but note that sexual stimulation is required for it to work.

✔️ Interaction

It's crucial to inform your doctor about all the medications, supplements, or herbal products you are currently taking or plan to take while using the Feel 5mg Tablet to avoid potential interactions. Certain medications may affect how Feel 5mg Tablet works or Feel 5mg Tablet itself may impact the effectiveness of other drugs taken simultaneously. Here are some important considerations:

Discuss All Medications: Provide a comprehensive list of all prescription and over-the-counter medications you are currently using or plan to use. This includes supplements and herbal products.

Planned Surgery or Vaccination: Inform your doctor if you have any scheduled surgeries or vaccinations. Your doctor may need to adjust your medication regimen accordingly.

Specific Medication Categories: Pay particular attention to medications in the following categories, as they may interact with Feel 5mg Tablet:

• Heart failure medications
• Anti-HIV medications
• Anti-infectives (antibiotics, antivirals, antifungals)
• Anti-diabetic medications
• Anti-asthmatic medications
• Pain relievers
• Immunomodulatory medications
• Medications for brain-related disorders

Nitrates: Avoid concurrent use of Feel 5mg Tablet with medications that contain nitrates. The combination can lead to severe hypotensive effects, causing dangerously low blood pressure. Nitrates are often used to treat chest pain (angina).

✔️ Pharmacology

• Allergic Reaction: You are allergic to tadalafil or any other component present in the tablet. Allergic reactions can be serious and may include symptoms like rash, itching, swelling, severe dizziness, or difficulty breathing.
• Use of Vasodilators: You are taking vasodilators such as amyl nitrate, nitrates, or medications containing riociguat. If you are unsure about whether your medication falls into this category, consult your doctor.
• Heart Problems: You have a known history of any heart problem, especially if you've experienced heart failure.
• Recent Cardiovascular Events: You have had a stroke in the past 6 months, a heart attack in the last 90 days, or if you've experienced breathlessness or chest pain during sexual activity. Using medications like Feel 5mg Tablet under these conditions can pose serious risks to your health.
• Liver Disorders: You have a known history of liver disorders. Tadalafil is metabolized in the liver, so liver problems can affect its clearance from your body.
• Low Blood Pressure: You have a history of low blood pressure. Feel 5mg Tablet can further lower blood pressure, potentially leading to complications.
• Eye Problems: You have a known history of eye problems such as retinitis pigmentosa, a genetic disorder that may cause vision loss.

✔️ Pregnancy & Lactation

Feel 5mg Tablet is not intended for use in pregnant and breastfeeding women.

✔️ Precautions & Warnings

• Pregnancy: Feel 5mg Tablet is not intended for use in pregnant women. It should be avoided during pregnancy.
• Breastfeeding: Feel 5mg Tablet is not intended for use in breastfeeding women. It's important to consult with a healthcare professional if you are breastfeeding and considering the use of this medication.
• Loss of Hearing: There have been reports of Feel 5mg Tablet causing a sudden decrease in hearing capabilities, along with ringing or buzzing sounds in the ears. If you experience a sudden decrease or loss of hearing while taking this medication, stop using it and consult your doctor.
• Counseling: Erectile dysfunction can have physical, psychological, or both physical and psychological causes. It's crucial to determine the underlying cause to develop an appropriate treatment plan. If the cause is primarily psychological or a combination of psychological and physical factors, psychological counseling may be recommended to achieve the best results.
• Driving and Operating Machinery: Feel 5mg Tablet may cause dizziness in some individuals. Therefore, it's advisable to avoid activities such as driving vehicles or operating machinery until you understand how this medication affects you. Your ability to perform such tasks may be temporarily impaired.
• Hypotension (Low Blood Pressure): Feel 5mg Tablet can cause a mild and short-lasting decrease in blood pressure. If you have low blood pressure, use this medicine with caution. It's important to discuss your blood pressure with your doctor before starting this medication, especially if you already have low blood pressure or are taking medications that can lower blood pressure.

✔️ Storage Conditions

• Keep Feel 5mg Tablet out of sight and reach of children
• Store Feel 5mg Tablet below 30°C